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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IGHG3
All Species:
6.67
Human Site:
Y337
Identified Species:
18.33
UniProt:
P01860
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P01860
XP_002348298
377
41287
Y337
S
D
G
S
F
F
L
Y
S
K
L
T
V
D
K
Chimpanzee
Pan troglodytes
XP_001168435
401
43934
Q352
V
E
W
E
S
S
G
Q
P
E
N
S
Y
N
T
Rhesus Macaque
Macaca mulatta
XP_001100439
438
47752
Y329
S
D
G
S
Y
F
L
Y
S
K
L
T
V
D
K
Dog
Lupus familis
XP_856442
233
24837
T194
K
Q
S
N
N
K
Y
T
A
S
S
Y
L
S
L
Cat
Felis silvestris
Mouse
Mus musculus
P03987
398
43911
E333
S
P
E
L
E
L
N
E
T
C
A
E
A
Q
D
Rat
Rattus norvegicus
P20759
326
35927
S287
D
G
S
Y
F
L
Y
S
K
L
N
V
K
K
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507984
588
64292
W537
D
E
E
L
E
G
L
W
T
T
I
S
V
F
I
Chicken
Gallus gallus
P01875
446
48155
S384
A
E
N
P
E
N
E
S
Y
V
A
Y
S
V
L
Frog
Xenopus laevis
NP_001083154
562
62536
F523
L
E
E
E
E
E
G
F
I
S
F
S
K
L
T
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
86.5
52
20.4
N.A.
55.5
56.7
N.A.
27.2
27.3
24.5
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
88.2
58.9
34.2
N.A.
66
70
N.A.
36.3
41
37
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
0
93.3
0
N.A.
6.6
6.6
N.A.
13.3
0
0
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
26.6
100
20
N.A.
13.3
13.3
N.A.
46.6
13.3
20
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
0
0
0
0
0
0
0
12
0
23
0
12
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% C
% Asp:
23
23
0
0
0
0
0
0
0
0
0
0
0
23
12
% D
% Glu:
0
45
34
23
45
12
12
12
0
12
0
12
0
0
12
% E
% Phe:
0
0
0
0
23
23
0
12
0
0
12
0
0
12
0
% F
% Gly:
0
12
23
0
0
12
23
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
12
0
12
0
0
0
12
% I
% Lys:
12
0
0
0
0
12
0
0
12
23
0
0
23
12
23
% K
% Leu:
12
0
0
23
0
23
34
0
0
12
23
0
12
12
23
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
12
12
12
12
12
0
0
0
23
0
0
12
0
% N
% Pro:
0
12
0
12
0
0
0
0
12
0
0
0
0
0
0
% P
% Gln:
0
12
0
0
0
0
0
12
0
0
0
0
0
12
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
34
0
23
23
12
12
0
23
23
23
12
34
12
12
0
% S
% Thr:
0
0
0
0
0
0
0
12
23
12
0
23
0
0
23
% T
% Val:
12
0
0
0
0
0
0
0
0
12
0
12
34
12
0
% V
% Trp:
0
0
12
0
0
0
0
12
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
12
12
0
23
23
12
0
0
23
12
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _